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Tricyclic antidepressants (TCAs) are well known tohave cardiac anticholinergic, and neuropsychiatric sideeffects. Indeed, it was observed that tumour cells have a peculiarity known as theWarburg effect; that is, they up-regulate glucose intake (characteristic of cells inhypoxia) even under normal oxygen conditions. The pre-sentation of this type of bone infection differs in children and adults.
The main cause of hearing loss in chil-dren is chronic middle ear infection. That is why you should get an EKG in older patients withsevere GI bleeding.
Evaluation for subclincial disease withcoronary calcium scoring is considered a IIa indicationin asymptomatic adults with diabetes 40 years of ageand older (27). (2002) Blood pressure and risk of headache: a pro-spective study of 22 685 adults in Norway.
These includeserum concentration of circulating T3, which depends onthe conversion rate of T4 to T3 in the peripheral organs;transport of thyroid hormones across the cell membrane byspecialized thyroid hormone transporters; and presence ofiodothyronine deiodinase enzymes, which activate orinactivate thyroid hormones.
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